Optima Health PLC (AIM:OPT, OTC:OHLTF, FRA:J3N) has lifted full-year revenue by around 15% to roughly £121 million, with adjusted EBITDA coming in around 10% ahead of expectations. In a trading update, the company said its £100 million acquisition of PAM Healthcare is already delivering, with £1.3 million of annualised cost synergies achieved by June. Read more
IP Group PLC (LSE:IPO) says portfolio company Istesso has begun dosing patients in a phase II trial of leramistat for muscle loss caused by rheumatoid arthritis. CEO Greg Smith calls it an important inflexion point, with the drug showing the potential to influence underlying tissue repair across multiple conditions. Read more
Poolbeg Pharma PLC (AIM:POLB) has been granted a European patent for POLB 001 in cancer immunotherapy-induced cytokine release syndrome, the most commercially significant approval in its CRS patent family to date. Interim data from the TOPICAL trial is expected later this summer. Read more
Gelion PLC (AIM:GELN, OTC:GELNF, FRA:X0S) has signed an exclusive commercial licence with Max-Planck-Innovation for nano-encapsulated sulfur cathode technology, formalising a deal that gives the company long-term global rights to the IP. CEO John Wood says the technology has "more than delivered" and commercial collaboration work can now begin. Read more
Active Energy Group PLC (AIM:AEG, OTCID:AEUSF) has signed a strategic distribution agreement with Fog Hashing to accelerate modular digital infrastructure deployment across the Gulf Cooperation Council countries. CEO Paul Elliott says the deal is "more than a supply agreement," giving the company the flexibility to rapidly upgrade sites for AI and high-performance computing. Read more
Galileo Resources PLC (AIM:GLR) has agreed to sell two Kalahari Copper Belt licences in Botswana to a Sandfire Resources subsidiary for $3 million upfront, with a potential success payment of up to $80 million if a significant copper reserve is defined. Sandfire has committed to spend $4.5 million on exploration within three years. Read more
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